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Flexeril Uses, Dosage, Side Effects & Warnings

Comparison studies have not shown one skeletal muscle relaxant to be superior to another. Cyclobenzaprine is the most heavily studied and has been shown to be effective for various musculoskeletal conditions. The sedative properties of tizanidine and cyclobenzaprine may benefit patients with insomnia caused by severe muscle spasms. Methocarbamol and metaxalone are less sedating, although effectiveness evidence is limited. Adverse effects, particularly dizziness and drowsiness, are consistently reported with all skeletal muscle relaxants. The potential adverse effects should be communicated clearly to the patient.

An interaction is when a substance changes the way a drug works. This can be harmful or prevent the drug from working well. Cyclobenzaprine oral tablet may cause drowsiness and dizziness. This is more likely to happen in the few hours after you take it. Severe CNS depression may result in significantly slowed breathing, over sedation, coma, and death.3If you are unable to stop abusing one or more substance, it’s time to seek help. Admitting your substance use has gotten out of control can save your life.

The dosage is based on your medical condition and response to treatment. This medication should only be used short-term (for 3 weeks or less) unless directed by your doctor. You are encouraged to report negative side effects of prescription drugs to the FDA. All patients suspected of an overdose with FLEXERIL should receive gastrointestinal decontamination. This should include large volume gastric lavage followed by activated charcoal.

  • Among the most dreaded toxicities linked with cyclical antidepressants, overdoses affect fast-acting sodium channels in the cardiac conduction system.
  • Although Flexeril doesn’t produce a euphoric high like many other drugs, people still misuse it due to its relaxing effects; many will increase dosages to amplify those effects.
  • It isn’t known exactly how this drug works to relax your muscles.
  • Do not take this drug for more than 3 weeks without talking to your doctor.
  • The medicine treats the condition by providing intermittent relief to the pain caused due to the spasms.

You might start to feel some of the effects of cyclobenzaprine within 20 to 30 minutes of taking it. The peak concentration varies, depending on what formulation you take. For example, the peak concentration for the extended-release pills is around seven hours. Even if you have insurance, the prices of Robaxin, Fexmid, Amrix, and other muscle relaxants may be cheaper through the BuzzRx discount program. You can get your BuzzRx card for free and start saving on muscle relaxants at a participating pharmacy near you right away.

Cyclobenzaprine’s Effectiveness Timeframe

To do so may increase the chance of serious side effects. Ask your pharmacist any questions you have about refilling your prescription. Do not flush medications down the toilet or pour them into a drain unless instructed to do so.

Flexeril and Diazepam are both used to treat muscle spasms. They belong to two different drug classes – muscle relaxant and benzodiazepine, flexeril and prozac reddit respectively. The only salient difference is that Valium has a higher potential to cause drug dependency than Flexeril.

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The immediate-release tablets last for about four to six hours, while the extended-release tablets last around 24 hours. UseCyclobenzaprine (Flexeril) exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended.

Centrally Acting Skeletal Muscle Relaxants and Associated Drugs

In preclinical research, cyclobenzaprine reduced skeletal muscle hyperactivity. Research indicates that it primarily acts within the central nervous system in the brain stem. The plasma concentration of cyclobenzaprine is increased in the elderly (see CLINICAL PHARMACOLOGY, Pharmacokinetics, Elderly).

If you’re taking Flexeril non-medically for a high—with or without other drugs—treatment for substance abuse can prevent you from suffering a dangerous overdose. Another telltale sign of Flexeril addiction is abusing the medication in combination with another substance to produce a greater sense of euphoria. Alcohol is commonly abused alongside muscle relaxers like Flexeril because the substances amplify each others’ effects, causing the individual to experience a more intense sedation or high. Flexeril is the brand name for Cyclobenzaprine, a prescription muscle relaxer that is similar to a class of Antidepressant drugs called Tricyclic Antidepressants. The generic form was first approved in 1977 and is sold in both immediate and extended release versions. Other side effects not listed may also occur in some patients.

Your risk may be higher if you also take certain other medicines that affect serotonin levels in your body. Clinicians should monitor for signs and symptoms of serotonin syndrome if the patient is taking other serotonergic drugs. In two case reports, the authors described patients who quickly developed serotonin syndrome after initiating cyclobenzaprine in the short term. A post-marketing surveillance program was carried out in 7607 patients with acute musculoskeletal disorders, and included 297 patients treated with FLEXERIL 10 mg for 30 days or longer. The overall effectiveness of FLEXERIL was similar to that observed in the double-blind controlled studies; the overall incidence of adverse effects was less (see ADVERSE REACTIONS).

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